San Antonio (21-11) bounced back from its first home loss in a month with a 91-80 road victory over Memphis on Friday, its sixth win in seven games overall.

The Spurs fell 100-98 to visiting Milwaukee on Tuesday, and now will try to avoid a second straight loss at the AT&T Center for the first time since going 0-3 to start the season. San Antonio is 12-6 on its home court.

Philadelphia (13-19) could be the ideal opponent for the Spurs to prevent that from happening. The 76ers have lost four in a row and 15 of their last 16 visits to San Antonio. They'll try for their first victory five years to the date of their last, 83-77 over the Spurs on Jan. 3, 2004.

Tim Duncan had 20 points and 10 rebounds, and Tony Parker added 19 points on Friday for San Antonio, which opened the game shooting 71 percent, including hitting its last eight shots in the first quarter.

While the Spurs' offense was the story early, their defense was the difference most of the night, holding the Grizzlies to 39.7 percent shooting from the field, including 2-for-14 from 3-point range.

"We needed our defense. We weren't making shots at a great rate (in the second half)," Spurs coach Gregg Popovich said. "Our defense helped us get through."

Parker and Duncan continue to play at an even higher level of late than their usual All-Star form. Parker is averaging 26.6 points in his last five games and Duncan 24.0 in his last four contests.

"They're paid to do that," Popovich said. "Usually the best players carry the team."

Parker had 27 points and five assists, but San Antonio lost 103-96 at Philadelphia on March 15 in the most recent meeting. The 76ers' victory snapped a three-game losing streak to the Spurs, who have won six of the last eight in the series.

Philadelphia enters this contest off a 96-86 loss at Dallas on Friday to fall to 1-4 on its season-high six-game road trip. Andre Iguodala scored 22 points, while Andre Miller had 17 and a season-high 11 rebounds for the 76ers, who are 6-11 on the road this season.

The Sixers led by as many 12 in the third quarter, but were hampered down the stretch by inconsistent offensive execution while the Mavericks made 11 of 15 shots in the fourth quarter.

"Our goal is to do 48 minutes, not 39 or 40 minutes. So we just have to do it a little longer," Philadelphia interim coach Tony DiLeo said. "We just have to figure out a way (to finish the game off) and I'm sure when we're full strength we'll have a little more depth to do that."

With Elton Brand out until at least the middle of the month with a shoulder injury, Iguodala and Miller continue to carry the load.

Iguodala has scored 50 points in his last two games, while Miller looks for another big night versus San Antonio after scoring 32 on 11-for-14 shooting against the Spurs in March.